The Cell Cycle, Its Phases and Checkpoints

2022年7月30日 — A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be ...

The key role of checkpoint proteins is to detect DNA damage and send a signal to delay cell cycle advance until the damaged chromosomes are repaired (Figure 1).

The mitotic spindle checkpoint occurs at the point in metaphase where all the chromosomes should/have aligned at the mitotic plate and be under bipolar tension.

Cell-cycle checkpoints prevent the transmission of genetic errors to daughter cells. There exist three major cell-cycle checkpoints; the G1/S checkpoint, the G2 ...

A checkpoint is a stage in the eukaryotic cell cycle at which the cell examines internal and external cues and decides whether or not to move forward with ...

A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be halted until ...

由 RE Shackelford 著作 · 1999 · 被引用 368 次 — The purpose of this review is to discuss the known signal transduction pathways that regulate cell cycle progression and the mechanisms cells employ to insure ...

由 KJ Barnum 著作 · 2014 · 被引用 724 次 — Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity, and fidelity of the major events of the cell cycle.

This checkpoint, also called the restriction checkpoint, takes place between the G1 and the S phase. The cell verifies that it is large enough to divide, that ...